Open Journal Systems

Cover Image

Cardiovascular Diseases Correlation with Antioxidants in Hilla City, Iraq

Mufeed J Ewadh, Monem M Alshok, Mena Y Abid


Cardiovascular disease (CVD) covers any disease of the circulatory system, namely the heart (cardio) or blood vessels (vascular), includes heart attack, angina and peripheral vascular heart disease, however antioxidants are vital substances that possess the ability to protect the body from damage caused by free radicals induce oxidative stress. This study aimed to find out the possible mechanisms of correlation between CVD and antioxidants. The results showed that total protein (TP),total antioxidant status (TAS), albumin levels, catalase (CAT), superoxide dismutase (SOD) have significance decreased in patients compared to control the group.  



Cardiovascular diseases, Antioxidants, Catalase, Total protein, Serum albumine

Full Text:



Urbaniak A, Molski M, SzelÄ…g M: Quantum-chemical calculations of the antioxidant properties of trans-p-coumaric acid and trans-sinapinic acid. Comput. Methods Sci. Technol 2012, 18:117-128.

Jozanov-Stankov O, Äurić J, Dobutović B, Isenović ER: Determination of total antioxidant status (TAS) as a biochemical parameter in control of workers' health. Archives of Biological Sciences 2009, 61:375-382.

Hamid A, Aiyelaagbe O, Usman L, Ameen O, Lawal A: Antioxidants: Its medicinal and pharmacological applications. Afr J Pure Appl Chem 2010, 4:142-151.

Szeląg M, Mikulski D, Molski M: Quantum-chemical investigation of the structure and the antioxidant properties of α-lipoic acid and its metabolites. Journal of molecular modeling 2012, 18:2907-2916.

Mikulski D, Szeląg M, Molski M, Górniak R: Quantum-chemical study on the antioxidation mechanisms of trans-resveratrol reactions with free radicals in the gas phase, water and ethanol environment. Journal of Molecular Structure: THEOCHEM 2010, 951:37-48.

Tietz NW: Clinical guide to laboratory tests: WB Saunders Co; 1995.

Herspring KF, Ferreira LF, Copp SW, Snyder BS, Poole DC, Musch TI: Effects of antioxidants on contracting spinotrapezius muscle microvascular oxygenation and blood flow in aged rats. Journal of Applied Physiology 2008, 105:1889-1896.

Hirai DM, Copp SW, Schwagerl PJ, Haub MD, Poole DC, Musch TI: Acute antioxidant supplementation and skeletal muscle vascular conductance in aged rats: role of exercise and fiber type. American Journal of Physiology-Heart and Circulatory Physiology 2011, 300:H1536-H1544.

Cohen G, Dembiec D, Marcus J: Measurement of catalase activity in tissue extracts. Analytical biochemistry 1970, 34:30-38.

Djoussé L, Rothman KJ, Cupples LA, Levy D, Ellison RC: Serum albumin and risk of myocardial infarction and all-cause mortality in the Framingham Offspring Study. Circulation 2002, 106:2919-2924.

Meisinger C, Heier M, Landgraf R, Happich M, Wichmann H-E, Piehlmeier W: Albuminuria, cardiovascular risk factors and disease management in subjects with type 2 diabetes: a cross sectional study. BMC health services research 2008, 8:226.

Ogawa T, Ishida H, Akamatsu M, Matsuda N, Fujiu A, Ito K, Ando Y, Nitta K: Progression of aortic arch calcification and all-cause and cardiovascular mortality in chronic hemodialysis patients. International urology and nephrology 2010, 42:187-194.

Fukai T, Folz RJ, Landmesser U, Harrison DG: Extracellular superoxide dismutase and cardiovascular disease. Cardiovascular research 2002, 55:239-249.

Franzini L, Ardigo D, Valtuena S, Pellegrini N, Del Rio D, Bianchi M, Scazzina F, Piatti P, Brighenti F, Zavaroni I: Food selection based on high total antioxidant capacity improves endothelial function in a low cardiovascular risk population. Nutrition, Metabolism and Cardiovascular Diseases 2012, 22:50-57.

Glorieux C, Dejeans N, Sid B, Beck R, Calderon PB, Verrax J: Catalase overexpression in mammary cancer cells leads to a less aggressive phenotype and an altered response to chemotherapy. Biochemical pharmacology 2011, 82:1384-1390.

Li H, Horke S, Förstermann U: Oxidative stress in vascular disease and its pharmacological prevention. Trends in pharmacological sciences 2013, 34:313-319.

Loenn ME, Dennis JM, Stocker R: Actions of "antioxidants" in the protection against atherosclerosis. Free Radical Biology and Medicine 2012, 53:863-884.



  • There are currently no refbacks.