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Impact of Wheat Bran Supplementation on Body Weight, Blood Pressure, Blood Glucose and Blood Lipids Among Obese Diabetic Women in Holy Makkah

Mohammad abd elmoneim Elmadbouly


Dietary fiber is part of a healthy diet and may exert a protective effect against several chronic diseases. A total of thirteen diabetic obese women with (BMI ≥30) were selected and instructed to consume 6 gm/d of wheat bran while they continued their usual diets for 8 weeks. Measures of body weight, BMI, blood pressure, blood glucose and blood lipids were undertaken and recorded at baseline, 4th and 8th weeks of the study for all subjects. Results showed that the mean body weight and BMI was reduced significantly (p˂0.05). The reduction in the blood lipid ( cholesterol, LDL, triglyceride) , blood glucose and the mean systolic and diastolic blood pressure after intervention weren’t significant (p>0.05).While the reduction in the (HDL) level after intervention was statistically significant. The findings from the present study support epidemiological evidence that addition of dietary fiber supplements to the diet has beneficial effects on body weight and controlling the obesity. While lipid profile, fasting blood glucose and blood pressure tend to lessen with using wheat bran for short period but not significantly.  



Wheat Bran, Supplementation, Body Weight, Blood Pressure, Blood Glucose, Blood Lipids, Obese Diabetic

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Hunt R, Fedorak R, Frohlich J, McLennan C, Pavilanis A: Therapeutic role of dietary fibre. Canadian Family Physician 1993, 39:897.

Pal S, Khossousi A, Binns C, Dhaliwal S, Ellis V: The effect of a fibre supplement compared to a healthy diet on body composition, lipids, glucose, insulin and other metabolic syndrome risk factors in overweight and obese individuals. British Journal of Nutrition 2011, 105:90-100.

Marlett JA, McBurney MI, Slavin JL: Position of the American Dietetic Association: health implications of dietary fiber. Journal of the American Dietetic Association 2002, 102:993-1000.

Verma AK, Banerjee R: Dietary fibre as functional ingredient in meat products: a novel approach for healthy living—a review. Journal of food science and technology 2010, 47:247-257.

Roma E, Adamidis D, Nikolara R, Constantopoulos A, Messaritakis J: Diet and chronic constipation in children: the role of fiber. Journal of pediatric gastroenterology and nutrition 1999, 28:169-174.

Anderson JW, Baird P, Davis Jr RH, Ferreri S, Knudtson M, Koraym A, Waters V, Williams CL: Health benefits of dietary fiber. Nutrition reviews 2009, 67:188-205.

Lattimer JM, Haub MD: Effects of dietary fiber and its components on metabolic health. Nutrients 2010, 2:1266-1289.

Anderson JW: Whole grains and coronary heart disease: the whole kernel of truth. The American journal of clinical nutrition 2004, 80:1459-1460.

Šramková Z, Gregová E, Šturdík E: Chemical composition and nutritional quality of wheat grain. 2009.

Slavin J: Whole grains and human health. Nutrition research reviews 2004, 17:99-110.

Wolever T, Miller JB: Sugars and blood glucose control. The American journal of clinical nutrition 1995, 62:212S-221S.

Jenkins DJ, Kendall CW, Augustin LS, Martini MC, Axelsen M, Faulkner D, Vidgen E, Parker T, Lau H, Connelly PW: Effect of wheat bran on glycemic control and risk factors for cardiovascular disease in type 2 diabetes. Diabetes care 2002, 25:1522-1528.

Liu S, Willett WC, Manson JE, Hu FB, Rosner B, Colditz G: Relation between changes in intakes of dietary fiber and grain products and changes in weight and development of obesity among middle-aged women. The American journal of clinical nutrition 2003, 78:920-927.

Rigaud D, Ryttig K, Angel L, Apfelbaum M: Overweight treated with energy restriction and a dietary fibre supplement: a 6-month randomized, double-blind, placebo-controlled trial. International journal of obesity 1990, 14:763-769.

Birketvedt G, Aaseth J, Florholmen J, Ryttig K: Long-term effect of fibre supplement and reduced energy intake on body weight and blood lipids in overweight subjects. Acta Medica (Hradec Kralove)/Universitas Carolina, Facultas Medica Hradec Kralove 1999, 43:129-132.

Kristensen M, Toubro S, Jensen MG, Ross AB, Riboldi G, Petronio M, Bügel S, Tetens I, Astrup A: Whole grain compared with refined wheat decreases the percentage of body fat following a 12-week, energy-restricted dietary intervention in postmenopausal women. The Journal of nutrition 2012, 142:710-716.

Bodinham CL, Hitchen KL, Youngman PJ, Frost GS, Robertson MD: Short-term effects of whole-grain wheat on appetite and food intake in healthy adults: a pilot study. British Journal of Nutrition 2011, 106:327-330.

Newby P, Maras J, Bakun P, Muller D, Ferrucci L, Tucker KL: Intake of whole grains, refined grains, and cereal fiber measured with 7-d diet records and associations with risk factors for chronic disease. The American journal of clinical nutrition 2007, 86:1745-1753.

Bortolotti M, Levorato M, Lugli A, Mazzero G: Effect of a balanced mixture of dietary fibers on gastric emptying, intestinal transit and body weight. Annals of nutrition & metabolism 2007, 52:221-226.

O'Neil CE, Zanovec M, Cho SS, Nicklas TA: Whole grain and fiber consumption are associated with lower body weight measures in US adults: National Health and Nutrition Examination Survey 1999-2004. Nutrition research 2010, 30:815-822.

Babio N, Balanza R, Basulto J, Bulló M, Salas-Salvadó J: Dietary fibre: influence on body weight, glycemic control and plasma cholesterol profile. Nutr Hosp 2010, 25:327-340.

Haripriya S, Premakumari S: Effect of wheat bran on diabetic subjects. Indian Journal of Science and Technology 2010, 3:284-286.

Ludwig DS, Pereira MA, Kroenke CH, Hilner JE, Van Horn L, Slattery ML, Jacobs Jr DR: Dietary fiber, weight gain, and cardiovascular disease risk factors in young adults. Jama 1999, 282:1539-1546.

Hollenbeck C, Coulston A, Reaven G: To what extent does increased dietary fiber improve glucose and lipid metabolism in patients with noninsulin-dependent diabetes mellitus (NIDDM)? The American journal of clinical nutrition 1986, 43:16-24.

Mani I, Mani UV: Effect of wheat bran supplementation on blood sugar, glycosylated protein and serum lipids in NIDDM subjects. Plant Foods for Human Nutrition 1987, 37:161-168.

Lithell H, Selinus I, Vessby B: Lack of effect of a purified bran preparation in men with low HDL cholesterol. Human nutrition. Clinical nutrition 1984, 38:309-313.

Roberts D, Truswell AS, Bencke A, Dewar HM, Farmakalidis E: The cholesterol-lowering effect of a breakfast cereal containing psyllium fibre. The Medical journal of Australia 1993, 161:660-664.

van Berge-Henegouwen G, Huybregts A, Van de Werf S, Demacker P, Schade R: Effect of a standardized wheat bran preparation on serum lipids in young healthy males. The American journal of clinical nutrition 1979, 32:794-798.

Kaul L, Nidiry J: High-fiber diet in the treatment of obesity and hypercholesterolemia. Journal of the National Medical Association 1993, 85:231.

Streppel MT, Arends LR, van't Veer P, Grobbee DE, Geleijnse JM: Dietary fiber and blood pressure: a meta-analysis of randomized placebo-controlled trials. Archives of Internal Medicine 2005, 165:150-156.

Behall KM, Scholfield DJ, Hallfrisch J: Whole-grain diets reduce blood pressure in mildly hypercholesterolemic men and women. Journal of the American Dietetic Association 2006, 106:1445-1449.



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