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Effect of Punica granatum and Syzygium cumini on body weights in ethylene glycol-induced kidney stone rats

Ayesha Tajammul, Nurul Kabir, Maryam Ahmad, Ali Sufyan


Punica granatum L. (PG) and Syzygium cumini L. (SC) are commonly used medicinal plants in Pakistan. All over the world, 80% of individuals show decrease in their body weight during kidney illness. In this study, PG and SC showed that during the treatment of the kidney stone disease they also exert positive effects on the body weights of rats having ethylene glycol-induced kidney stone. Body weights of all groups including control, KS model, PG and SC rats were assessed by relative body weight. Rats having ethylene glycol-induced kidney stone showed a decrease in body weight as compared with control group. PG and SC groups at doses of 250 and 350g showed gradual increase in body weight during the illness and exhibited that both plant’s products have nutritional values which play a key role in the maintenance and improvement in health by increasing the body weights. Comparing the effect of PG and SC on body weight, we found that SC fruits extract at dose of 250mg showed better effect on the body weight of rats than PG flowers extract.


Body weight, Punica granatum L, Syzygium cumini L, Kidney stones.

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