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Current status of Indian Medicinal Plants with Immunomodulatory potential - A Review

Kaliappan Ilango, Ananth kumar Kammalla, Govind Prasad Dubey, Aruna Agrawal


Every country in the world has lists of herbal remedies for the treatment of diseases and different other unwanted conditions in humans. Ayurveda is one of the traditional systems of medicine practiced in India and Sri Lanka and can be traced back to 6000 B.C. Modulation of immune responses to alleviate the diseases has been of interest for many years and the concept of 'Rasayana' in Ayurveda is based on related principles. Rasayana is helpful to improve immunity and is normally advised during the degenerative phase of life, which starts from around 45 years in both males and females. Some of the medicinal plants valued in Ayurvedic Rasayana like Asparagus racemosus, Achillea wilhelmsii, Acacia catechu, Adhatoda vasica, Aloe vera, Amophophallus companulatus, Azadirachta indica, Bauhinia variegate, Bergenia stracheyi, Capparis zeylanica, Carica papaya, Chlorophytum arundinaeceum, Centella asiatica, Curcuma longa, Dioscorea alata, Enicostemma axillare, Justica spicigera, Mangifera indica, Madhuca longifolia, Ocimum sanctum, Ricinus communis, Tinospora cordifolia, Toxicodendron pubescens, Zingiber officinale etc., are evaluated for their therapeutic potential and have been scientifically investigated with promising results. A number of plant-based principles have been isolated with potential immunomodulatory activity that can explain and justify their use in traditional medicine in the past and can form the basis for further research in the future as well. This work shall hopefully encourage researchers to undertake further work on medicinal plants with potential immunomodulatory activity.


Immunomodulation, Rasayana, Herbal plants

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